Inclusion of Tissue

Research Tissue Repository

Updated April 2008

The Tissue Repository will collect prospective cases. Tissues will be collected as left over from surgical specimens after diagnostic pathology examination is finished. If not used for tissue banking, these tissues would eventually be discarded.

A Tissue Repository Request must be completed to initiate the tissue/data request process.

Tissue Repository pathologists will review all cases considered for inclusion into the Repository. At the time of entry, pathologists will review all surgical pathology reports and histological sections for each subject to accurately categorize each case, and to assign and categorize appropriate paraffin blocks, for the use of the resource. Pathologists will perform a detailed evaluation of all the slides submitted for each case, not only the case submitted as adjacent section, but all of the slides submitted for diagnostic purpose also.

There will be a data sheet for the pathologist to record all pertinent pathology parameters. The Data Management Specialist will include all this information in the Tissue Repository database of that subject: tumor type and subtype, margins of resection, size of tumor, grade, pathological stage, satellite lesions, lymph node status, adjacent pre-malignant lesions, lymphovascular invasion, perineural invasion, neoadjuvant therapy effects, and organ site-specific pathologic staging items.